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How does MDMA affect the brain?

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 How does MDMA affect the brain? Dopamine—produces increased energy/activity and acts in the reward system to reinforce behaviors Norepinephrine—increases heart rate and blood pressure, which are particularly risky for people with heart and blood vessel problems Serotonin—affects mood, appetite, sleep, and other functions. It also triggers hormones that affect sexual arousal and trust. The release of large amounts of serotonin likely causes the emotional closeness, elevated mood, and empathy felt by those who use MDMA . Other health effects include: nausea muscle cramping involuntary teeth clenching blurred vision chills sweating MDMA’s effects last about 3 to 6 hours, although many users take a second dose as the effects of the first dose begin to fade. Over the course of the week following moderate use of the drug, a person may experience: irritability impulsiveness and aggression depression sleep problems anxiety memory and attention problems decreased appetite decreased interest in